Unexplained infertility — San Francisco, CA
Unexplained infertility means the standard workup — ovulation, tubes, semen analysis, ovarian reserve — found no cause. It is a diagnosis of exclusion, and it is common. It does not mean nothing is wrong; it means today's tests can't see what is.
The evidence-backed path is usually stepped: a few cycles of ovulation induction with IUI, then IVF if those fail. Reasonable clinics differ on how fast to escalate — what matters is that the plan has a defined number of attempts and a decision point, not open-ended repetition.
Fertility clinics in San Francisco, CA
The share shown for each clinic is the percentage of its cycles with an unexplained-factor diagnosis.
- Pacific Fertility Center ranked #59 nationally · 5% of cycles: unexplained factor
- Laurel Fertility Care ranked #245 nationally · 25% of cycles: unexplained factor
- UCSF Center for Reproductive Health ranked #109 nationally · 11% of cycles: unexplained factor
- Spring Fertility-San Francisco ranked #22 nationally · 13% of cycles: unexplained factor
- Reproductive Medicine Associates of Northern California ranked #97 nationally · 0.5% of cycles: unexplained factor
- Kindbody-San Francisco ranked #185 nationally · 14% of cycles: unexplained factor
- Kaiser Permanente Center for Reproductive Health ranked #142 nationally · 25% of cycles: unexplained factor
What to ask at a consult
- What did my workup actually rule out, and what wasn't tested?
- How many IUI cycles before IVF, and what success rate do you expect from each step for my age?
- At what point would you change the plan?
Costs are a first-class question for treatment — see what IVF costs and how to pay less and whether insurance must cover treatment in California.
Outcome data: CDC NASS 2022 Final ART Summary. Success rates vary with patient age, diagnosis, and clinic patient-selection practices; comparisons across clinics may not be meaningful (CDC). This page is general information, not medical advice.